Di 31.10.2017 16:06:44 CET by BrunO

Genetics


University of Michigan News Service | Genetic study of house dust mites demonstrates reversible evolution

In evolutionary biology, there is a deeply rooted supposition that you can't go home again: Once an organism has evolved specialized traits, it can't return to the lifestyle of its ancestors. ANN ARBO


Regulators Discover a Hidden Viral Gene in Commercial GMO Crops

by Jonathan Latham and Allison Wilson How should a regulatory agency announce they have discovered something potentially very important about the safety of products they have been approving for over twenty years? In the course of analysis to identify potential allergens in GMO crops, the European Food Safety Authority (EFSA) ...


Science and Social Control: Political Paralysis and the Genetics Agenda

By Jonathan Latham, PhD (Originally posted July 31st and lost after a DDOS (electronic) attack) Variations in individual “educational attainment” (essentially, whether students complete high school or college) cannot be attributed to inherited genetic differences. That is the finding of a new study reported in Science magazine (Rietveld et al. ...


Evolution too slow to keep up with climate change

Many vertebrate species would have to evolve about 10,000 times faster than they have in the past to adapt to the rapid climate change expected in the next 100 years, a new study has found.


Genomics, Society and Policy, Vol - 1746-5354-5-1-1.pdf


EHP – The Environment Within: Exploring the Role of the Gut Microbiome in Health and Disease


PLOS ONE: Complete Genes May Pass from Food to Human Blood

PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.


Genetic Polymorphism and Toxicology—With Emphasis on Cytochrome P450


The Failing Animal Research Paradigm for Human Disease

by John J. Pippin, M.D., F.A.C.C. “The history of cancer research has been a history of curing cancer in the mouse. We have cured mice of cancer for decades—and it simply didn’t work in humans.” This statement was made by Richard Klausner, M.D., former director of the National Cancer Institute, ...


Genes found in nature yield 1918-like virus with pandemic potential


Entwicklung des Neandertalers: Zuerst kam das Gesicht - Wissen - Tagesspiegel

17 Schädel haben Forscher aus der „Knochengrube“ in Nordspanien geborgen. Die Funde helfen, die Evolution der Frühmenschen zu entwirren.


Public (Mis)understanding of News about Behavioral Genetics Research: A Survey Experiment


Our Inner Viruses: Forty Million Years In the Making – Phenomena

Each year, billions of people get infected with viruses--with common ones like influenza and cold viruses, and rarer ones like polio and Ebola. The viruses don't stay all that long inside of us. In...


Retrovirology | Abstract | The decline of human endogenous retroviruses: extinction and survival

Endogenous Retroviruses (ERVs) are retroviruses that over the course of evolution have integrated into germline cells and eventually become part of the host genome. They proliferate within the germline of their host, making up ~5% of the human and mouse genome sequences. Several lines of evidence have suggested a decline in the rate of ERVs integration into the human genome in recent evolutionary history but this has not been investigated quantitatively or possible causes explored.


An Unlikely Driver of Evolution: Arsenic - NYTimes.com

A new study suggests that people who live in the Atacama Desert are more resistant to arsenic than other people, thanks to natural selection.


EHP – The Genetic Architecture of Arsenic Metabolism Efficiency: A SNP-Based Heritability Study of Bangladeshi Adults


Proposed Moratorium on Genetic Modification of Human Germ Cells | Knoepfler Lab Stem Cell Blog


Scientists sound alarm over DNA editing of human embryos : Nature News & Comment

Experts call for halt in research to work out safety and ethics issues.


CGS : Public interest group calls for strengthening global policies against human germline modification

“No researcher has the moral warrant to flout the globally widespread policy agreement against altering the human germline.”


Genome Editing: Time to Ask the Tough Questions | Silvia Camporesi

"What are the moral implications of genome editing?" is the question that has been posed by the Nuffield Council on Bioethics regarding the new CRISPR-Cas9 mediated germ-line genome editing technique, which allows targeted modification of D...


Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort


The Twin Research Debate in American Criminology


Growing Doubt: a Scientist’s Experience of GMOs

Jonathan R. Latham, PhD By training, I am a plant biologist. In the early 1990s I was busy making genetically modified plants (often called GMOs for Genetically Modified Organisms) as part of the research that led to my PhD. Into these plants we were putting DNA from various foreign organisms, ...


Des manipulations génétiques d’embryons humains autorisées au Royaume-Uni

Une équipe londonienne pourra utiliser Crispr-Cas9, un outil d’ingénierie du génome, pour désactiver des gènes sur des embryons obtenus en surplus lors de fécondations in vitro.


UK scientists gain licence to edit genes in human embryos : Nature News & Comment

Team at Francis Crick Institute permitted to use CRISPR–Cas9 technology in embryos for early-development research.


God’s Red Pencil? CRISPR And The Three Myths Of Precise Genome Editing

by Jonathan Latham, PhD For the benefit of those parts of the world where public acceptance of biotechnology is incomplete, a public relations blitz is at full tilt. It concerns an emerging set of methods for altering the DNA of living organisms. “Easy DNA Editing Will Remake the World. Buckle ...


Gene sharing between Epstein-Barr virus and human immune response genes. - PubMed - NCBI

Immunol Res. 2016 Jul 15. [Epub ahead of print]


Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children — NEJM

Original Article from The New England Journal of Medicine — Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children


Hundreds of genes seen sparking to life two days after death | New Scientist

The discovery that many genes are still working up to 48 hours after death has implications for organ transplants, forensics and our very definition of death


Epigenetic marks may help assess toxic exposure risk - someday | Science News

Exposure to things in the environment may change chemical tags on DNA and proteins, but it's still unclear how to use that data to assess health risks.


Genetics Is Giving Way to a New Science of Life

by Jonathan Latham, PhD Test your understanding of the living world with this simple question. What kind of biomolecule is found in all living organisms? If your answer is “DNA”, you are incorrect. The mistake is very forgiveable though. The standard English-language biology education casts DNA (DeoxyriboNucleic Acid) as the ...


Researchers ID New Mechanism for Keeping DNA Protein in Line | Berkeley Lab


Female Mouse Embryos Actively Remove Male Reproductive Systems


Living on Earth: Genetics and the Environment

There’s been a paradigm shift in the field of genetics. Instead of relying solely on DNA and inheritance, the field of epigenetics now demonstrates how environmental factors can also determine diseases in our future, and in our children and grandchildren’s future. Host Bruce Gellerman talks with epigeneticist Michael Skinner, a professor at Washington State University.



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